Compare Products: 345 Relief Cream vs PDRN Pink Peptide Serum

Dr. Althea

345 Relief Cream

Mid-range
$24 / 50ml — $0.48/ml
Medicube

PDRN Pink Peptide Serum

Mid-range
$37 / 30ml — $1.23/ml

Who It's Designed For

Dr. Althea
  • Those with compromised or sensitized skin barriers
  • Users recovering from skin procedures or environmental damage
  • Sensitive skin types seeking a fragrance-free calming cream
  • People who want centella benefits with added antioxidant support
  • Those looking for a non-greasy barrier repair cream
Medicube
  • Those seeking peptide-based anti-aging with PDRN
  • Users who want a lightweight serum for morning and evening use
  • People interested in K-beauty award-winning products
  • Those looking for brightening alongside anti-aging benefits
  • Users who enjoy a subtle scented serum experience

Key Ingredients

Dr. Althea

Centella Asiatica Extract, Resveratrol, Ceramide NP, Panthenol, Madecassoside

Medicube

Rose PDRN (Sodium DNA), 5-Type Peptide Complex, Niacinamide (4.4-5.4%), Adenosine, Hydrolyzed Collagen

Product Composition

29% similarity (16 ingredients in common)

Shared Ingredients
waterbutylene glycolglycerincetyl ethylhexanoateniacinamide12-hexanediolglyceryl stearatesorbitan olivatesodium hyaluronatetromethamineethylhexylglycerindisodium edtasorbitan sesquioleatepolyglyceryl-10 lauratecaprylyl glycol
Only in Dr. Althea (21)
cetearyl alcoholhydrogenated lecithinstearic acidcetearyl olivatedimethiconeceramide nppanthenolcentella asiatica extractmadecassosideasiaticosideasiatic acidmadecassic acidresveratrolallantoinbeta-glucandipotassium glycyrrhizatetocopherolcaprylic/capric triglyceridehydroxyethyl ureaxanthan gumcarbomer
Only in Medicube (19)
dipropylene glycolpvm/ma copolymerglycereth-26adenosineisopropyl myristateubiquinonefragrancepolyisobutenehydrolyzed collagenatelocollagensalmon egg extractcyanocobalaminmelia azadirachta leaf extractmelia azadirachta flower extractcurcuma longa (turmeric) root extractocimum sanctum leaf extractcorallina officinalis extractpalmitoyl pentapeptide-4palmitoyl tetrapeptide-7

User Feedback Patterns

Dr. Althea
Effective for redness and irritation

Users frequently report reduced redness and calmer skin within days of use. Popular among those with rosacea-prone or post-procedure skin.

Non-greasy for a barrier cream

Multiple reviewers note the texture is lighter than expected for a repair cream. Absorbs well and works under makeup.

Reliable daily moisturizer

Many users report using this as their primary moisturizer long-term, not just for recovery periods. Consistent performance across seasons.

Mild results for severe barrier damage

Some users with significantly compromised barriers note the cream helped but was not sufficient on its own. Needed pairing with other barrier products.

Medicube
Pleasant texture with firmness boost

Users describe a bouncy, lightweight gel that leaves skin feeling firmer and more hydrated. Makeup artists and beauty editors have highlighted the glow it provides.

Quick absorption for layering

The serum absorbs rapidly, making it easy to layer under moisturizer and sunscreen without pilling.

Fragrance is divisive

Some users appreciate the subtle rose scent. Others wish for a fragrance-free version, especially for sensitive skin use.

View Full Product Details

Related Comparisons