Dr. Althea 345 Relief Cream
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Formulation Summary
A centella-focused barrier repair cream built around four centella-derived actives: madecassoside, asiaticoside, asiatic acid, and madecassic acid. The formula pairs these with resveratrol as an antioxidant, ceramide NP for lipid barrier support, and panthenol for soothing. Designed as a recovery cream for sensitized or compromised skin.
Dr. Althea isolates four specific compounds from Centella Asiatica rather than relying on a single extract. This targeted approach delivers madecassoside and asiaticoside for calming, plus asiatic acid and madecassic acid for collagen support. Resveratrol adds antioxidant activity uncommon in centella creams. Ceramide NP and panthenol round out the barrier repair function. The formula includes dimethicone for occlusion but avoids fragrance and essential oils.
Quick Facts
Designed For
- •Those with compromised or sensitized skin barriers
- •Users recovering from skin procedures or environmental damage
- •Sensitive skin types seeking a fragrance-free calming cream
- •People who want centella benefits with added antioxidant support
- •Those looking for a non-greasy barrier repair cream
May Not Suit
- •Users sensitive to fatty alcohols (cetearyl alcohol is present)
- •Those who avoid silicones (contains dimethicone)
- •People seeking a lightweight gel-cream texture
- •Users looking for brightening or anti-aging as primary benefits
Key Ingredients
| Ingredient | Concentration | Function |
|---|---|---|
| Centella Asiatica Extract | — | Provides the base calming and repair activity. Contains multiple active compounds that support wound healing and reduce inflammation. Listed in the middle of the ingredient list. |
| Madecassoside | — | Isolated centella compound with strong anti-inflammatory properties. Research shows it promotes collagen synthesis and helps calm irritated skin. |
| Resveratrol | — | Polyphenol antioxidant typically found in grape skins. Provides antioxidant protection and has some anti-inflammatory activity. Uncommon in centella-focused formulas. |
| Ceramide NP | — | Skin-identical lipid that helps restore the barrier. Works alongside the centella actives to rebuild compromised skin. |
| Panthenol | — | Provitamin B5. Attracts moisture and supports skin healing. Widely used in dermatological products for its soothing properties. |
The Formulation Explained
Four centella compounds
Rather than using a single centella extract, this formula includes four isolated compounds: madecassoside, asiaticoside, asiatic acid, and madecassic acid. Each has slightly different activity. Madecassoside and asiaticoside focus on calming. Asiatic acid and madecassic acid support collagen production. The '345' in the product name references this multi-compound centella approach.
Resveratrol as antioxidant
Resveratrol is an unusual choice for a centella cream. Most barrier repair creams use tocopherol or green tea as their antioxidant. Resveratrol has research supporting anti-inflammatory and antioxidant activity, though its stability in cream formulations depends on packaging and pH. The brand does not disclose concentration.
Barrier lipid support
Ceramide NP and squalane-adjacent lipids provide structural barrier support. These work at the lipid matrix level to help rebuild the skin barrier. Panthenol and allantoin add soothing hydration. This combination positions the cream as a recovery product rather than a simple moisturizer.
What is not in here
The formula excludes fragrance, essential oils, and parabens. It does include dimethicone, which some users prefer to avoid. No L-ascorbic acid or retinoids are present, keeping the formula focused on calming rather than active treatment.
Ingredients to Know
Common humectant and solvent. Listed second, indicating moderate to high concentration. Generally well tolerated.
Fatty alcohol emulsifier. Not a drying alcohol. May trigger reactions in individuals specifically sensitive to fatty alcohols.
Silicone that forms a breathable occlusive layer. Helps lock in moisture. Some users prefer silicone-free formulas.
Listed fifth in the ingredient list, suggesting a moderate concentration. Provides brightening and barrier support alongside the centella actives.
User Feedback Patterns
Full INCI List
37 ingredients · Click "Show full list" to view
About Dr. Althea
The brand lists full INCI ingredients but does not disclose specific concentrations for most actives. The '345' naming convention references the number of centella compounds used but is not tied to disclosed percentages.
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Sources
- • https://www.amazon.com/Dr-Althea-Relief-Cream-Centella/dp/B08XQ7FYCX
- • https://incidecoder.com/products/dr-althea-345-relief-cream
- • https://skinsort.com/products/dr-althea/345-relief-cream
- • https://www.yesstyle.com/en/dr-althea-345-relief-cream-50ml/info.html/pid.1098837849
- • https://global.oliveyoung.com/product/detail?prdtNo=GA240300267
Last updated: 2026-03
Rating Scales
Comedogenicity (0-5)
Likelihood of clogging pores. 0 = won't clog, 1-2 = low, 3 = moderate, 4-5 = high.
Irritancy (0-5)
Potential for skin irritation. 0 = non-irritating, 1-2 = low, 3 = moderate, 4-5 = high.
Ratings based on published ingredient studies. Individual reactions may vary.